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Shortage Support

We all hear and talk about 'drug shortages' - but what do they really mean? A drug shortage is when a drug manufacturer is unable to supply a drug in order to meet the demands of consumers; meaning it is on back-order or completely out-of-stock. This can be caused by manufacturing delays, difficulty obtaining raw ingredients, discontinuation of the drug, or a sudden increase in the demand of a medication. During drug shortages, pharmaceutical compounding becomes an essential solution. Defined as the practice of preparing customized medications that are not otherwise commercially available, pharmaceutical compounding not only allows providers the opportunity to explore patient-tailored plans, but is also a critical safety net that allows providers to fill medication needs during product unavailability, like drug shortages.

To support compounding pharmacies and hospitals, Medisca closely monitors global shortages and proactively prepares formulas with step-by-step instructions on how to compound a given medication in need. As the bread and butter of compounding, formulas are one of the most sought after support during a drug shortage, and a priority for Medisca to assist on. On this web page is a consolidated list of formulas to support the preparation of medications that may currently or have recently been on shortage. All formulas are freely accessible. Prior to compounding any of these formulations, it is the pharmacist’s responsibility to ensure that they are aware of the current availability status of the commercial products and are compliant with all Provincial, State, Territory and Federal compounding regulations.

25%
1 in 4 drugs sold annually are impacted by drug shortages in Canada1
170+
Medisca Formulas to support current and former Canadian Drug shortages, freely accessible below.


API(s) and Strength(s)Route of DeliveryDosage FormBaseFormula
Acetaminophen 100 mg per mL Oral Liquid Medisca Oral Suspend + Medisca Oral Syrup F 004 369
Acetaminophen 100 mg per mL Oral Liquid ORA Blend® F 009 744
Acetaminophen 225 mg Oral Troche Medisca Troche Base F 006 584
Acetaminophen 300 mg Rectal Suppositories Medisca SPG Supposi-Base™ F 004 387
Acetaminophen 32 mg per mL Oral Liquid Medisca Oral Suspend + Medisca Oral Syrup F 009 757
Acetaminophen 32 mg per mL Oral Liquid ORA Blend® F 009 755
Acetaminophen 80 mg per mL Oral Liquid ORA Blend® F 009 756
Acetaminophen 80 mg per mL Oral Liquid Medisca Oral Suspend + Medisca Oral Syrup F 009 758
Acetaminophen 80 mg per mL Oral Liquid Methylcellulose Gel (1%) F 009 778
Acyclovir 200 mg per 5 mL Oral Liquid Medisca Oral Mix F 006 141
Acyclovir 400 mg Oral Capsules Medisca CapsuBlend®-S F 004 361
Acyclovir 500 mg per 10 mL Injection Liquid Sterile Water for Injection, USP F 002 333
Alendronate Sodium 91 mg per 75 mL Oral Liquid Purified Water, USP F 004 718
Alprostadil 40 mcg per mL Intrapenile Liquid Sterile Water for Injection, USP F 001 676
Aminophylline 25 mg per mL Injection Liquid Sterile Water for Injection, USP F 000 740
Amiodarone Hydrochloride 50 mg per mL Oral Liquid Purified Water, USP + Syrup (Simple), NF F 003 363
Amiodarone Hydrochloride 50 mg per mL Intravenous Liquid Sterile Water for Injection, USP F 008 641
Amlodipine Besylate 1 mg per mL Oral Liquid Medisca Oral Mix F 006 038
Amoxicillin 125 mg per 5 mL, Potassium Clavulanate 31.25 mg per 5mL Oral Liquid Medisca Oral Mix F 009 779
Amoxicillin 250 mg per 5 mL Oral Liquid Medisca Oral Mix F 009 743
Amoxicillin 250 mg per 5 mL Oral Liquid Purified Water, USP F 000 338
Amoxicillin 250 mg per 5 mL, Potassium Clavulanate 62.5 mg per 5mL Oral Liquid ORA Blend® F 009 782
Amoxicillin 400 mg per 5 mL Oral Liquid Purified Water, USP F 003 572
Amoxicillin 400 mg per 5 mL G-Tube Liquid Purified Water, USP F 003 573
Amoxicillin 400 mg per 5 mL, Potassium Clavulanate 57 mg per 5mL Oral Liquid Medisca Oral Syrup + Medisca Oral Suspend F 009 783
Amoxicillin Trihydrate 1004.4 mg, Potassium Clavulanate 148.9 mg per 5 mL Oral Liquid Medisca Oral Suspend + Medisca Oral Syrup F 002 594
Amphetamine A 2.5 mg, Amphetamine S 2.5 mg, Dextroamphetamin... Oral Liquid Medisca Oral Suspend + Medisca Oral Syrup F 003 206
Atenolol 2 mg per mL Oral Liquid Medisca Oral Mix F 003 975
Atomoxetine Hydrochloride 5 mg per mL Oral Liquid Syrup (Simple), NF F 000 553
Atropine Sulfate Ophthalmic Ointment  Petrolatum (White), USP F 001 769
Azithromycin 200 mg Oral Gummy Gels Medisca Gum Base (Gelatin) F 008 183
Azithromycin 200 mg per 5 mL Oral Liquid Medisca Oral Mix F 006 142
Azithromycin 200 mg per 5 mL Oral Liquid Medisca Oral Suspend + Medisca Oral Syrup F 004 074
Azithromycin 200 mg per 5 mL Oral Liquid Purified Water, USP F 004 026
Azithromycin Dihydrate 105 mg per mL Intravenous Liquid Sterile Water for Injection, USP F 005 067
Bethanechol Chloride 25 mg Oral Capsules Cellulose (Microcrystalline), NF F 003 676
Brimonidine Tartrate 0.05% Ophthalmic Liquid Sterile Water for Injection, USP F 007 350
Bupivacaine 0.25%, Epinephrine 1 in 200 000 Injection Liquid Sterile Water for Irrigation, USP F 008 657
Bupivacaine 0.25, Epinephrine 1 in 200 000 Injection Liquid Sterile Water for Irrigation, USP F 008 656
Bupivacaine 0.5%, Epinephrine 1 in 200 000 Injection Liquid Sterile Water for Irrigation, USP F 008 665
Bupivacaine 0.5, Epinephrine 1 in 200 000 Injection Liquid Sterile Water for Irrigation, USP F 008 664
Bupropion Hydrochloride 150 mg per 5 mL Oral Liquid Medisca Oral Suspend + Medisca Oral Syrup F 001 555
Cabergoline 500 µg per mL Oral Liquid Propylene Glycol, USP F 006 902
Carbidopa 25 mg, Levodopa 100 mg Oral Capsules Hypromellose (4000 CPS) Methocel E4M, USP + Cellulose (Microcrystalline), NF F 004 228
Cefazolin 2 g per 100 mL Intravenous Liquid Dextrose Injection, USP (Sterile, Cefazolin reconstitution liquid) F 003 712
Cefixime (trihydrate) Oral Liquid Oral suspend F 006 077
Cefprozil 250 mg per 5 mL Oral Liquid Medisca Oral Mix F 009 749
Ceftazidime 100 mg per mL Intravenous Liquid Sterile Water for Injection, USP F 008 724
Ceftriaxone Sodium 20 mg per mL Intravenous Liquid Sterile Water for Injection, USP F 008 725
Cephalexin 250 mg per 5 mL Oral Liquid Purified Water, USP F 000 340
Cetirizine Hydrochloride 1 mg per mL Oral Liquid Purified Water, USP F 003 714
Chloroquine Phosphate 161 mg Oral Capsules Lactose (Monohydrate), USP F 002 310
Chloroquine phosphate 250 mg Oral Capsules Lactose (Monohydrate), USP F 000 437
Chloroquine Phosphate 50 mg per mL Oral Liquid Medisca Oral Syrup F 001 767
Chloroquine Phosphate 80.5 mg per 5 mL Oral Liquid Medisca Oral Suspend + Medisca Oral Syrup F 001 479
Ciprofloxacin 250 mg per 5 mL Oral Liquid Purified Water, USP + Syrup (Simple), NF F 002 579
Cisatracurium Besylate 2.68 mg per mL Injection Liquid Sterile Water for Injection, USP F 008 666
Clarithromycin 150 mg per 5 mL Oral Liquid Medisca Oral Mix F 006 143
Clindamycin 150 mg per mL Injection Liquid Sterile Water for Injection, USP F 008 829
Clindamycin Hydrochloride 40.72 mg Oral Capsules Lactose (Monohydrate), USP F 001 928
Clopidogrel 75 mg per 5 mL Oral Liquid Medisca Oral Suspend + Medisca Oral Syrup F 008 824
Cyclosporin 100 mg per mL Oral Liquid Olive Oil, NF F 004 615
Denatonium Benzoate 0.0135% Inhalation Liquid Sterile Water for Injection, USP F 008 674
Denatured Alcohol (95%),USP 80% Topical Liquid Purified Water, USP F 008 630
Dexamethasone 4 mg per mL Oral Liquid Medisca Oral Mix F 006 154
Dextrose 5% Intravenous Liquid Sterile Water for Injection, USP F 008 690
Diazepam 0.5% Rectal Gel  Hypromellose (4000 CPS) Methocel E4M, USP + Benzyl Alcohol, NF + Propylene Glycol, USP + Purified Water, USP F 005 175
Diclofenac Sodium 0.1% Ophthalmic Liquid Sterile Water for Injection, USP F 006 637
Diclofenac Sodium 50 mg Oral Capsules Medisca CapsuBlend®-H F 004 676
Diltiazem Hydrochloride 10 mg per mL Oral Liquid Purified Water, USP F 006 148
Dimercaprol 100 mg per mL Intramuscular Liquid Peanut Oil, NF F 008 909
Dorzolamide 2, Timolol 0.5 Ophthalmic Liquid Sterile Water for Injection, USP F 008 793
Enalapril Maleate 1 mg per mL Oral Liquid Medisca Oral Mix F 006 034
Enoxaparin Sodium 150 mg per mL Intravenous Liquid Sterile Water for Injection, USP F 008 696
Epinephrine 1 mg per mL Injection Liquid Sterile Water for Injection, USP F 002 207
Epinephrine 10 mcg per mL Intravenous Liquid Sodium Chloride 0.9% for Injection, USP (Sterile) F 004 337
Erythromycin 0.5% Ophthalmic Ointment  Petrolatum, USP F 004 057
Erythromycin 200 mg per mL Injection Liquid Sterile Water for Injection, USP F 003 152
Erythromycin Ethylsuccinate 46.8 mg per mL Oral Liquid Syrup (Simple), NF F 004 001
Famotidine 10 mg per mL Intramuscular Liquid Sterile Water for Injection, USP F 004 918
Famotidine 40 mg per 10 mL Oral Liquid Medisca Oral Suspend + Medisca Oral Syrup F 001 452
Fluvoxamine Maleate 50 mg per 5 mL Oral Liquid Medisca Oral Suspend + Medisca Oral Syrup F 002 593
Folic Acid 1 mg per mL Oral Liquid Medisca Oral Syrup F 003 545
Folic Acid 5 mg per mL injection Liquid Sterile Water for Injection, USP F 003 199
Haloperidol 0.5 mg Oral Capsules Medisca CapsuBlend®-P F 008 147
Haloperidol 0.5 mg Oral Rapid-Dissolve Tablets Medi-RDT™ Base F 007 801
Haloperidol 1 mg Oral Capsules Medisca CapsuBlend®-P F 008 150
Haloperidol 1 mg Oral Rapid-Dissolve Tablets Medi-RDT™ Base F 007 800
Haloperidol 10 mg Oral Capsules Medisca CapsuBlend®-P F 008 153
Haloperidol 2 mg Oral Capsules Medisca CapsuBlend®-P F 008 151
Haloperidol 5 mg Oral Capsules Medisca CapsuBlend®-P F 008 152
Haloperidol 5 mg per mL Intramuscular Liquid Sterile Water for Injection, USP F 004 920
Heparin 1000 Units per mL Injection Liquid Sterile Water for Injection, USP F 001 514
Heparin 5000 Units per mL Injection Liquid Sterile Water for Injection, USP F 001 515
Hydralazine Hydrochloride 10 mg per mL Intravenous Liquid Sterile Water for Injection, USP F 004 313
Hydrochlorothiazide 13 mg per mL Oral Liquid Medisca Oral Suspend + Medisca Oral Syrup F 003 362
Hydrocortisone 90 mg Mucoadhesive Rectal Suppositories Medisca NovaFilm™ Gel Base + Medisca SPG Supposi-Base™ F 008 455
Hydromorphone HCL 0.1 mg per mL Intravenous Liquid Sodium Chloride 0.9% for Injection, USP (Sterile) F 003 715
Hydromorphone HCL 0.2 mg per mL Epidural Liquid Sodium Chloride 0.9% for Injection, USP (Sterile, Preservative Free) F 003 716
Hydromorphone HCL 0.2 mg per mL Epidural Liquid Sodium Chloride 0.9% for Injection, USP (Sterile, Preservative Free) F 003 683
Hydromorphone HCL 1 mg per mL Intravenous Liquid Sodium Chloride 0.9% for Injection, USP (Sterile) F 003 631
Hydromorphone HCL 1 mg per mL Epidural Liquid Sodium Chloride 0.9% for Injection, USP (Sterile, Preservative Free) F 003 649
Hydromorphone HCL 1 mg per mL Intravenous Liquid Sodium Chloride 0.9% for Injection, USP (Sterile) F 003 650
Hydromorphone HCL 2 mg per mL Intravenous Liquid Sterile Water for Injection, USP F 005 004
Hydromorphone Hydrochloride 1 mg per mL Oral Liquid Purified Water, USP F 009 075
Hydromorphone Hydrochloride 1 mg per mL Oral Liquid Medisca Oral Mix F 009 078
Hydromorphone Hydrochloride 5 mg per mL Intravenous Liquid Sodium Chloride 0.9% for Injection, USP (Sterile) F 004 336
Hydroxychloroquine Sulfate 100 mg per 5 mL Oral Liquid Medisca Oral Suspend + Medisca Oral Syrup F 003 495
Hydroxychloroquine Sulfate 100 mg per 5 mL Oral Liquid Medisca Oral Suspend + Medisca Oral Syrup F 008 654
Hydroxychloroquine Sulfate 200 mg Oral Capsules Medisca CapsuBlend®-S F 008 628
Hydroxychloroquine Sulfate 25 mg per mL Oral Liquid Medisca Oral Mix F 006 870
Hydroxychloroquine Sulfate 25 mg per mL Oral Liquid Medisca Oral Mix SF F 006 871
Hydroxyzine Hydrochloride 50 mg Oral Capsules Medisca CapsuBlend®-S F 004 961
Ibuprofen 100 mg per 5 mL Oral Liquid Purified Water, USP F 003 629
Ibuprofen 100 mg per 5 mL Oral Liquid Medisca Methylcellulose Gel (1%) F 000 285
Ibuprofen 100 mg per 5 mL Oral Liquid ORA Blend® F 009 768
Ibuprofen 100 mg per 5 mL Oral Liquid Medisca Oral Suspend + Medisca Oral Syrup F 009 769
Ibuprofen 160 mg Oral Gummy Gels Medisca Gelatin Gum Base F 003 692
Ibuprofen 400 mg per 5 mL Oral Liquid Medisca Methylcellulose Gel (1%) F 002 954
Ibuprofen 600 mg Rectal Suppositories Medisca SPG Supposi-Base™ F 004 389
Isosorbide Mononitrate 60 mg per 5 mL Oral Liquid Medisca Oral Suspend + Medisca Oral Syrup F 001 915
Ketamine HCl 11.5 mg per mL Intravenous Liquid Sterile Water for Injection, USP F 007 516
Ketamine Hydrochloride 11.5 mg per mL Intravenous Liquid Sterile Water for Injection, USP F 002 682
Lansoprazole 30 mg per 5 mL Oral Liquid Purified Water, USP + Syrup (Simple), NF F 000 302
Leuprolide Acetate 1 mg per 0.2 mL Injection Liquid Bacteriostatic Sodium Chloride Injection, USP F 004 822
Levetiracetam 250 mg per 5 mL Oral Liquid Medisca Oral Suspend + Medisca Oral Syrup F 001 812
Linezolid 100 mg per 5 mL Oral Liquid Medisca Oral Suspend + Medisca Oral Syrup F 003 820
Lorazepam 2 mg per mL Intramuscular Liquid Propylene Glycol, USP F 004 989
Losartan Potassium 6.25 mg per 5 mL Oral Liquid Medisca Oral Suspend + Medisca Oral Syrup F 002 332
Meloxicam 30 mg per mL Oral Liquid Purified Water, USP F 007 665
Meperidine HCL 50 mg per mL Intravenous Liquid Sterile Water for Injection, USP F 004 594
Meropenem 50 mg per mL Injection Liquid Sterile Water for Injection, USP F 008 727
Metformin Hydrochloride 250 mg Oral Capsules Medisca CapsuBlend®-H F 004 814
Methadone Hydrochloride 10 mg per mL Injection Liquid Sterile Water for Injection, USP F 001 938
Methotrexate 25 mg per mL Intramuscular Liquid Sterile Water for Injection, USP F 004 923
Metoprolol Tartrate 1 mg per mL Subcutaneous Liquid Sterile Water for Injection, USP F 004 902
Metoprolol Tartrate 3 mg per 0.5 mL Oral Liquid Medisca Oral Mix F 006 150
Metronidazole 5 mg per mL Intravenous Liquid Sterile Water for Injection, USP F 008 739
Midazolam 5 mg per mL Intravenous Liquid Sterile Water for Injection, USP F 004 993
Misoprostol 100 mcg Oral Capsules Medisca CapsuBlend®-S F 004 851
Mycophenolate Mofetil 50 mg per mL Oral Liquid Medisca Oral Suspend + Medisca Oral Syrup F 004 106
Nifedipine 5 mg per 2.5 mL Oral Liquid Medisca Oral Mix F 006 151
Nifedipine 5 mg per 2.5 mL Oral Liquid Medisca Oral Suspend + Medisca Oral Syrup F 003 693
Nizatidine 15 mg per mL Oral Liquid Medisca Oral Suspend + Medisca Oral Syrup F 002 802
Nystatin 100,000 IU per mL Oral Liquid Medisca Oral Mix F 008 084
Nystatin 100,000 IU per mL Oral Liquid Medisca Oral Syrup F 008 096
Nystatin 100,000 IU per mL Oral Liquid Methylcellulose Gel (1%) + Syrup (Simple), NF F 008 097
Nystatin 100,000 IU per mL Oral Liquid Methylcellulose Gel (1%) F 008 098
Nystatin 100,000 IU per mL Mucoadhesive Oral Liquid Medisca NovaFilm™ Gel Base + Medisca Oral Mix SF F 008 262
Olmesartan Medoxomil 10 mg per 2.5 mL Oral Liquid Medisca Oral Suspend F 007 375
Ondansetron Hydrochloride 2.5 mg per mL Injection Liquid Sterile Water for Injection, USP F 004 976
Oseltamivir 12 mg per mL Oral Liquid Medisca Oral Syrup + Medisca Oral Suspend F 001 067
Paroxetine 20 mg Oral Troche Medisca Troche Base F 007 656
Penicillin Potassium G 40 000 000 IU per 100mL Injection Liquid Sterile Water for Injection, USP F 003 325
Penicillin V Potassium 300 mg per 5 mL Oral Liquid Purified Water, USP F 000 339
Pindolol 5 mg Oral Capsules Medisca CapsuBlend®-P F 008 795
Piperacillin 200 mg, Tazobactam 25 mg per mL Intravenous Liquid Sterile Water for Injection, USP F 008 819
Potassium Acetate 40 mEq per 20 mL Intravenous Liquid Sterile Water for Injection, USP F 004 810
Pravastatin Sodium 1 mg per mL Oral Liquid Medisca Oral Suspend + Medisca Oral Syrup F 005 627
Prednisolone 15 mg per 5 mL Oral Liquid Medisca Oral Mix F 006 159
Pregabalin 50 mg per 5 mL Oral Liquid Medisca Oral Suspend F 007 382
Propofol 10 mg per mL Intravenous Liquid Sterile Water for Injection, USP F 008 701
Rabeprazole Sodium 20 mg per 5 mL Oral Liquid Medisca Oral Suspend + Medisca Oral Syrup F 001 472
Ramipril 10 mg per 5 mL Oral Liquid Medisca Oral Suspend + Medisca Oral Syrup F 003 381
Ranitidine 150 mg per 5 mL Oral Liquid Medisca Oral Mix F 006 163
Ribavirin 200 mg Oral Capsules Medisca CapsuBlend®-S F 009 847
Ribavirin 200 mg per mL Oral Liquid Medisca Oral Mix F 009 846
Rifampin 75 mg Oral Capsules Lactose (Monohydrate), USP F 003 091
Ropinirole Hydrochloride 5 mg per 5ml Oral Liquid Purified Water, USP F 000 247
Ropivacaine Hydrochloride 5 mg per mL Injection Liquid Sterile Water for Injection, USP F 008 728
Saccharin Sodium 0.83% Inhalation Liquid Sterile Water for Injection, USP F 008 675
Sertraline 100 mg per 5 mL Oral Liquid Medisca Oral Syrup SF F 008 758
Sildenafil 40 mg Oral Troche Medisca Troche Base F 006 288
Simvastatin 16 mg per mL Oral Liquid Medisca Oral Suspend + Medisca Oral Syrup F 003 536
Sodium Bicarbonate 150 mEq per 1000 mL Intravenous Liquid Dextrose 5% Injection, USP (Sterile, Preservative Free) F 004 848
Sodium Bicarbonate 8.4% Injection Liquid Sterile Water for Injection, USP F 001 512
Sodium Chloride 0.9% Injection Liquid Sterile Water for Injection, USP F 002 239
Succinylcholine Chloride 20 mg per mL Intravenous Liquid Sterile Water for Injection, USP F 004 628
Sumatriptan 100 mg Oral Capsules Medisca CapsuBlend®-S F 008 796
Tadalafil 23 mg Oral Rapid-Dissolve Tablets Medi-RDT™ Base F 007 784
Terbinafine Hydrochloride 250 mg per mL Oral Liquid Medisca Oral Suspend + Medisca Oral Syrup F 002 943
Testosterone 100 mg per mL Intramuscular Liquid Sesame Oil, NF F 004 571
Timolol Maleate 0.50% Ophthalmic Liquid Sterile Water for Injection, USP F 000 095
Topiramate 25 mg per 5 mL Oral Liquid Medisca Oral Mix F 006 140
Trazodone Hydrochloride 100 mg Oral Capsules Medisca CapsuBlend®-S F 006 770
Valsartan 40 mg Oral Capsules Cellulose (Microcrystalline), NF F 008 827
Zolpidem Tartrate 5 mg per 5 mL Oral Liquid Medisca Oral Suspend + Medisca Oral Syrup F 003 282

1. Health Canada. (2022). Drug shortages in Canada and their implications on public drug plans, 2017/18 to 2019/20. Government of Canada. https://www.canada.ca/en/patented-medicine-prices-review/services/npduis/analytical-studies/posters/capt2022-drug-shortages-canada.html.

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